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Giuseppe Nappi Selected Research

Secondary Headache Disorders

6/2015Triptan use in Italy: Insights from administrative databases.
10/2014Combined effect of common gene variants on response to drug withdrawal therapy in medication overuse headache.
5/2013Factors associated with a negative outcome of medication-overuse headache: a 3-year follow-up (the 'CARE' protocol).
10/2012An electronic diary on a palm device for headache monitoring: a preliminary experience.
10/2012Acute reduction of anandamide-hydrolase (FAAH) activity is coupled with a reduction of nociceptive pathways facilitation in medication-overuse headache subjects after withdrawal treatment.
8/2011Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study.
11/2010Role of 2 common variants of 5HT2A gene in medication overuse headache.
12/2009A narrative review on the management of medication overuse headache: the steep road from experience to evidence.
4/2009From drug-induced headache to medication overuse headache. A short epidemiological review, with a focus on Latin American countries.

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Giuseppe Nappi Research Topics

Disease

32Migraine Disorders (Migraine)
01/2019 - 01/2003
24Headache (Headaches)
10/2019 - 06/2004
21Pain (Aches)
11/2017 - 01/2003
12Parkinson Disease (Parkinson's Disease)
05/2010 - 03/2002
9Hyperalgesia
11/2017 - 08/2002
9Secondary Headache Disorders
06/2015 - 04/2009
7Brain Ischemia (Cerebral Ischemia)
12/2014 - 09/2004
5Ischemia
07/2012 - 12/2002
4Migraine without Aura (Common Migraine)
05/2015 - 01/2002
4Alzheimer Disease (Alzheimer's Disease)
12/2012 - 10/2003
4Dyskinesias (Dyskinesia)
05/2010 - 07/2006
3Tension-Type Headache (Tension Headache)
01/2019 - 04/2006
3Epilepsy (Aura)
04/2016 - 10/2013
3Headache Disorders (Headache Syndromes)
10/2012 - 09/2005
3Primary Headache Disorders
12/2010 - 04/2010
2Craniocerebral Trauma (Head Injury)
12/2018 - 06/2004
2Sleep Initiation and Maintenance Disorders (Insomnia)
12/2018 - 10/2003
2Stroke (Strokes)
12/2014 - 10/2003
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/2014 - 07/2012
2Substance-Related Disorders (Drug Abuse)
10/2014 - 09/2011
2Chronic Pain
10/2013 - 08/2002
2Cognitive Dysfunction
12/2012 - 10/2006
2Cluster Headache (Cluster Headaches)
10/2012 - 08/2008
2Inflammation (Inflammations)
08/2010 - 12/2006
2Brain Injuries (Brain Injury)
01/2009 - 01/2009
2Mood Disorders (Mood Disorder)
06/2003 - 05/2002
1Prescription Drug Overuse
12/2018
1Snoring
12/2018
1Low Back Pain (Lumbago)
10/2013
1Reperfusion Injury
07/2012
1Neuroinflammatory Diseases
07/2012

Drug/Important Bio-Agent (IBA)

16Pharmaceutical PreparationsIBA
10/2019 - 03/2002
14Nitroglycerin (Dynamite)FDA LinkGeneric
11/2017 - 01/2003
11Tryptamines (Triptans)IBA
06/2015 - 01/2003
8Formaldehyde (Formol)FDA Link
11/2017 - 01/2003
5Biomarkers (Surrogate Marker)IBA
04/2016 - 09/2005
5Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2015 - 08/2002
5Analgesics (Analgesic Drugs)IBA
10/2013 - 01/2003
4Glutamic Acid (Glutamate)FDA Link
11/2017 - 03/2006
4Biological ProductsIBA
07/2014 - 09/2010
4Serotonin (5 Hydroxytryptamine)IBA
11/2010 - 07/2003
3Type A Botulinum Toxins (Botox)FDA Link
06/2018 - 06/2003
3CytokinesIBA
11/2017 - 01/2003
3Hormones (Hormone)IBA
12/2016 - 09/2004
3EndocannabinoidsIBA
03/2014 - 04/2011
3Estrogens (Estrogen)FDA Link
02/2013 - 09/2006
3EnzymesIBA
10/2012 - 12/2002
3ProstaglandinsIBA
01/2007 - 01/2003
2Botulinum Toxins (Botulinum Toxin)IBA
06/2018 - 12/2006
2Messenger RNA (mRNA)IBA
11/2017 - 01/2015
2Protein Isoforms (Isoforms)IBA
12/2014 - 07/2012
2Receptor for Advanced Glycation End ProductsIBA
12/2014 - 07/2012
2Glutamate Receptors (Glutamate Receptor)IBA
03/2014 - 04/2006
2Apolipoprotein E4IBA
12/2012 - 10/2006
2anandamide (arachidonylethanolamide)IBA
10/2012 - 04/2011
2Nitric Oxide DonorsIBA
05/2011 - 01/2007
2NF-kappa B (NF-kB)IBA
02/2011 - 10/2005
2Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
09/2010 - 05/2002
2Cholinesterase Inhibitors (Anticholinesterases)IBA
08/2009 - 10/2003
2Levodopa (L Dopa)FDA LinkGeneric
05/2009 - 01/2008
2Dopamine Receptors (Dopamine Receptor)IBA
05/2009 - 05/2002
2Transcription Factors (Transcription Factor)IBA
01/2008 - 10/2005
2Pain-FreeIBA
12/2007 - 01/2002
2Oxidopamine (6 Hydroxydopamine)IBA
01/2007 - 12/2006
2Antipsychotic Agents (Antipsychotics)IBA
07/2006 - 01/2004
2N-Methylaspartate (NMDA)IBA
04/2006 - 08/2002
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2003 - 08/2002
2nimesulide (Aulin)IBA
01/2003 - 08/2002
1ErgotaminesIBA
10/2019
1FlunarizineIBA
01/2019
1Combined Oral ContraceptivesIBA
12/2018
1Complex MixturesIBA
12/2018
1Hypnotics and Sedatives (Sedatives)IBA
12/2018
1Kynurenic Acid (Kynurenate)IBA
11/2017
1Contraceptive Agents (Contraceptives)IBA
12/2016
1Monoacylglycerol LipasesIBA
12/2015
1Dichlorodiphenyldichloroethane (DDD)IBA
06/2015
1Calcitonin Gene-Related PeptideIBA
05/2015
1Peptides (Polypeptides)IBA
05/2015
1Calcitonin (Calcitonin, Eel)FDA LinkGeneric
05/2015
1Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2014
1AntibodiesIBA
12/2014
1N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA
12/2014
1Brain-Derived Neurotrophic Factor (BDNF)IBA
10/2014
1CB2 Cannabinoid ReceptorIBA
03/2014
1frovatriptan (Allegro)FDA Link
10/2013
1valylvaline (Val-Val)IBA
10/2013
1Opioid Analgesics (Opioids)IBA
10/2013
1methionylmethionine (Met-Met)IBA
10/2013
1Morphine (MS Contin)FDA LinkGeneric
10/2013
1tramiprosateIBA
12/2012
1fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
10/2012
1Illicit Drugs (Recreational Drugs)IBA
10/2012
1HydrolasesIBA
10/2012
1onabotulinum toxin AIBA
08/2011

Therapy/Procedure

15Therapeutics
10/2014 - 01/2005
2Deep Brain Stimulation
11/2009 - 08/2009
2Complementary Therapies (Alternative Medicine)
08/2008 - 04/2006
2Drug Prescriptions
03/2005 - 03/2002
1CARE protocol
05/2013